Coagulation Factor X anticorps

N° du produit ABIN6568380

Cet anticorps anti-Coagulation Factor X est un anticorps Lapin Polyclonal détectant Coagulation Factor X dans IF. Adapté pour Humain et Souris.

Aperçu rapide pour Coagulation Factor X anticorps (ABIN6568380)

Antigène: Coagulation Factor X (F10)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coagulation Factor X est non-conjugé

Application: Immunofluorescence (IF)

Détail du produit anti-Coagulation Factor X anticorps

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human F10 (NP_000495.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Coagulation Factor X

Antigène: Coagulation Factor X (F10)

Autre désignation: F10

Sujet: This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.

Poids moléculaire:

Observed_MW: 75kDa

Calculated_MW: 54kDa

ID gène: 2159

UniProt: P00742